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Phospholipase A2 - Role and Function in Inflammation (Paperback, Softcover reprint of the original 1st ed. 1990)
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Phospholipase A2 - Role and Function in Inflammation (Paperback, Softcover reprint of the original 1st ed. 1990)
Series: Advances in Experimental Medicine and Biology, 275
Expected to ship within 10 - 15 working days
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This volume in the Advances in Experimental Medicine and Biology
Series is dedicated to developing an overall view of the "state-of
the-art" of knowledge in the field of phospholipase A2 and to
exploring the role and function of this enzyme in various
inflammatory diseases. This book grew out of two major symposia on
phospholipase A2 held in 1989: I). "Phospholipase A2:
Pathophysiological Role of Soluble and Membrane-Bound Enzymes"
organized by Dr. Doug Morgan and Dr. Ann Welton of Hoffmann-La
Roche and sponsored by the New York Academy of Sciences (January
24, 1989). II). "Release and Function of Phospholipase A2 from
Inflammatory Cells" organized by Dr. Patrick Wong and Dr. Edward
Dennis at the FASEB meeting in New Orleans (March 22, 1989).
Readers will find exciting advances in our understanding of the
structure, function and molecular biology of phospholipase A2
research which is presented in this volume. The elucidation of gene
structures of phospholipase A2 should lead to new insights and new
approches in the control and regulation of the enzyme activity.
This is primary to better understanding the function of
phospholipase A2 and the determination of its activity in cellular
and animal systems. Of great importance is the development of
animal models for inflammatory disease in order to evaluate the
role of phospholipase A2 and its inhibitors. We are convinced that
this volume will be an excellent reference that surveys this field
in which numerous investigators are currently actively at work.
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