Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Metastatic Cancer: Clinical and Biological Perspectives (Hardcover)
Loot Price: R3,562
Discovery Miles 35 620
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Metastatic Cancer: Clinical and Biological Perspectives (Hardcover)
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Most cancer deaths are a result of metastasis. The spread of a
primary tumor to colonize neighboring and distant organs is the
relentless endgame that defines the neoplastic process. Patients
who have been diagnosed with cancer are treated to prevent both the
recurrence of the tumor at the site of origin and metastasis that
would re-stage them as advanced stage IV cancer. Historically and
still with some types of cancer, stage IV is perceived by patients
as "terminal." Fortunately, recent molecular therapies have
extended the lives of patients with advanced cancer and
reassuringly people living with metastatic disease increasingly
visit our clinics. What is the path forward? Given that the
consilience of science and medicine is a dynamic art from which
therapies arise, it would be misguided to consider any single work
adequate at capturing the horizon for research. So with humility we
constructed this text as primer for scientists. It begins with a
broad introduction to the clinical management of common cancers.
This is intended to serve as a foundation for investigators to
consider when developing basic science hypotheses. Unquestionably,
medical and surgical care of cancer patients reveals biology and
dictates how novel therapeutics will ultimately be evaluated in
clinical trials. The second section of this text offers provocative
and evolving insights that underscore the breadth of science
involved in the elucidation of cancer metastasis biology. The text
concludes with information that integrates scientific and clinical
foundations to highlight translational research. This book serves
as a framework for scientists to conceptualize clinical and
translational knowledge on the complexity of disease that is
metastatic cancer.
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