Key features: Serves as a standard reference for researchers,
teachers and students of various disciplines such as Fisheries
Science, Marine Biology, Life Sciences, Biotechnology, Natural
Products, and Pharmacy, their libraries, and as a valuable guide
for pharmaceutical companies involved in the development of new
drugs from marine sponges Presents the taxonomy, common name,
global distribution, and habitat of 250 species of marine sponges
Provides the diagnostic features and pharmaceutical compounds
(along with their chemical structure and activities) of 450 species
of marine sponges Includes more than 500 detailed illustrations
Biology and Ecology of Pharmaceutical Marine Sponges is the first
comprehensive book of its kind written by scientists from both the
Marine Biology and Pharmacy disciplines to fill the long-felt need
for a marine natural products book devoted exclusively to sponges.
Sponges are the most primitive multicelled animals that have
existed for 700 - 800 million years. Despite their wide range of
functional roles, not much is known about them. Marine sponges are
responsible for more than 5,300 pharmaceutical products and some
species have the potential to provide future drugs to prevent and
treat important medical conditions such as cancer, a range of viral
diseases, malaria, and inflammatory diseases. Nucleosides derived
from sponges were the basis for the synthesis of Ara-C, the first
marine-derived anticancer agent, currently used in the routine
treatment of patients with leukemia and lymphoma. Marine sponges
are the potential sources of many unique metabolites with
anticancer,anti-inflammatory, antibiotic, antiviral, antimalarial,
and immune or neurosuppressive properties. Although many bioactives
have been discovered in marine sponges, only a few of these
compounds have been commercialized. This book hopes to change that,
providing the taxonomy, common name, global distribution, habitat,
diagnostic features and pharmaceutical compounds (along with their
chemical structure and activities) of 450 species of marine
sponges, accompanied by high-quality illustrations. The book should
be a standard reference for students, researchers and teachers of
disciplines such as Fisheries Science, Marine Biology,
Biochemistry, Biotechnology and Pharmacy and a valuable guide for
pharmaceutical companies involved in the development of new drugs
from marine sponges.
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