This textbook, aimed at advanced undergraduate and graduate
students, introduces the basic knowledge required for nanomedicine
and nanotechnology, and emphasizes how the combined use of
chemistry and light with nanoparticles can serve as treatments and
therapies for cancer. This includes nanodevices,
nanophototherapies, nanodrug design, and laser heating of
nanoparticles and cell organelles. In addition, the book covers the
emerging fields of nanophotonics and nanoplasmonics, which deal
with nanoscale confinement of radiation and optical interactions on
a scale much smaller than the wavelength of the light. The
applications of nanophotonics and nanoplasmonics to biomedical
research discussed in the book range from optical biosensing to
photodynamic therapies.Cutting-edge and reflective of the
multidisciplinary nature of nanomedicine, this book effectively
combines knowledge and modeling from nanoscience, medicine,
biotechnology, physics, optics, engineering, and pharmacy in an
easily digestible format. Among the topics covered in-depth are:*
The structure of cancer cells and their properties, as well as
techniques for selective targeting of cancer and gene therapy.*
Nanoplasmonics: Lorentz-Mie simulations of optical properties of
nanoparticles and the use of plasmonic nanoparticles in diagnosis
and therapy.* Nanophotonics: short and ultrashort laser pulse
interactions with nanostructures, time and space simulations of
thermal fields in and around the nanobioparticles, and nanoclusters
heated by radiation.* Modeling of soft and hard biological tissue
ablation by activated nanoparticles, as well as optical, thermal,
kinetic, and dynamic modeling.* Detection techniques, including the
design and methods of activation of nanodrugs and plasmon resonance
detection techniques.* Design and fabrication of nanorobots and
nanoparticles.* Effective implementation of nanotherapy
treatments.* Nanoheat transfer, particularly the heating and
cooling kinetics of nanoparticles.* ...and more!Each chapter
contains a set of lectures in the form of text for student readers
and PowerPoints for use by instructors, as well as homework
exercises. Selected chapters also contain computer practicums,
including Maple codes and worked-out examples. This book helps
readers become more knowledgeable and versant in nanomedicine and
nanotechnology, inspires readers to work creatively and go beyond
the ideas and topics presented within, and is sufficiently
comprehensive to be of value to research scientists as well as
students.
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