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Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology

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Protein Misfolding in Neurodegenerative Diseases - Mechanisms and Therapeutic Strategies (Hardcover) Loot Price: R6,169
Discovery Miles 61 690
Protein Misfolding in Neurodegenerative Diseases - Mechanisms and Therapeutic Strategies (Hardcover): Robert D. E Sewell

Protein Misfolding in Neurodegenerative Diseases - Mechanisms and Therapeutic Strategies (Hardcover)

Robert D. E Sewell

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Loot Price R6,169 Discovery Miles 61 690 | Repayment Terms: R578 pm x 12*

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Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.

A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding

Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.

General

Imprint: Crc Press
Country of origin: United States
Release date: December 2007
First published: December 2007
Editors: Robert D. E Sewell
Dimensions: 234 x 156mm (L x W)
Format: Hardcover
Pages: 592
ISBN-13: 978-0-8493-7310-7
Categories: Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
LSN: 0-8493-7310-7
Barcode: 9780849373107

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