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Pharmacological Studies of Dillenia Indica L. (Paperback)
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Pharmacological Studies of Dillenia Indica L. (Paperback)
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Total price: R1,480
Discovery Miles: 14 800
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This study protocol, we have investigated antimicrobial, cytotoxic,
antidiarrhoeal, analgesic and CNS depressant activity of the
ethanolic extracts of leaves and fruits of Dillenia indicia. In the
test of antimicrobial and antibacterial activity, it had been
confirmed that leaf and fruit extract have inhibitory property for
the growth of micro organism and it was also established by the
test of MIC. The LC50 values of Dillenia indica in brine shrimp
lethality bioassay were found significant. The plant parts showed
antidiarrhoeal activity which was measured by castor oil induced
method and charcoal plug method. All the samples showed significant
analgesic activity. In the hole cross test for CNS depressant
studies, the extracts also showed a decrease in locomotion in the
test animals and in the open field test, the crude ethanolic
extract of leaves and roots of D. indica showed a noticeable
decrease in locomotion in the test animals. In the pentobarbitone
induced hypnosis test, the crude ethanolic extract of leaves of D.
indica at the doses 400 mg/kg significantly induced the sleep and
also prolonged the duration of sleeping time in test animals as
compared to control.
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