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Books > Medicine > Clinical & internal medicine > Haematology
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Chronic Myeloid Leukemia (Hardcover, 1st ed. 2016)
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Chronic Myeloid Leukemia (Hardcover, 1st ed. 2016)
Series: Hematologic Malignancies
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This book provides state-of-the-art reviews of key issues and
recent developments relating to chronic myeloid leukemia (CML),
acquainting the reader with advances in research, treatment, and
promotion of public health. Among the management topics addressed
are the choices, advantages, and pitfalls of first-, second-, and
third-line treatments; the European LeukemiaNet recommendations;
management of adverse effects of tyrosine kinase inhibitors (TKI);
management of CML blast crisis; management of pregnancy in the
context of CML; the role of hematopoietic cell transplantation; the
current experience with TKI discontinuation; and the value of
interferon in improving the outcome of TKI treatment. Various
aspects of relevance to treatment outcome are discussed, including
prognostic scores, molecular monitoring (principles and
interlaboratory standardization), and response-related predictors
of survival. Furthermore, updates are provided on the increasing
prevalence of CML and its implications and on the changing cost of
care for CML, taking into account the forthcoming impact of
availability of generic imatinib.
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