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Mosaicism in Human Skin - Understanding Nevi, Nevoid Skin Disorders, and Cutaneous Neoplasia (Hardcover, 2014 ed.)
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Mosaicism in Human Skin - Understanding Nevi, Nevoid Skin Disorders, and Cutaneous Neoplasia (Hardcover, 2014 ed.)
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Mosaicism is a powerful biologic concept, originally developed from
the study of plants and animals, and is the necessary basis for the
explanation of numerous human skin disorders. This lavishly
illustrated book presents, for the first time, a comprehensive
overview of the strikingly manifold patterns and peculiarities of
mosaic skin disorders. It is structured in a straightforward,
reader-friendly way that will help the dermatologist to understand
the underlying molecular mechanisms of skin disorders in order to
further improve the treatment outcome. The first two parts of the
book are devoted to the mechanisms and patterns of cutaneous
mosaicism, with explanation of genomic and epigenetic mosaicism and
description of the six archetypal patterns, including the lines of
Blaschko, as well as less well defined or as yet unclassifiable
patterns. In the third part, the various mosaic skin disorders are
examined in depth, including nevi, allelic and non-allelic
didymosis, other binary genodermatoses, mosaic manifestations of
autosomal dominant skin disorders, and nevoid skin disorders. The
book concludes with a note on neoplastic skin lesions, examining
models of tumorigenesis.
General
Imprint: |
Springer-Verlag
|
Country of origin: |
Germany |
Release date: |
December 2013 |
First published: |
2014 |
Authors: |
Rudolf Happle
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Dimensions: |
254 x 178 x 19mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
229 |
Edition: |
2014 ed. |
ISBN-13: |
978-3-642-38764-7 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Dermatology
|
LSN: |
3-642-38764-0 |
Barcode: |
9783642387647 |
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