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Books > Medicine > Clinical & internal medicine > Hepatology
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Clinical Research in Gastroenterology 1 (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R1,428
Discovery Miles 14 280
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Clinical Research in Gastroenterology 1 (Paperback, Softcover reprint of the original 1st ed. 1987)
Expected to ship within 10 - 15 working days
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The last decade has seen tremendous developments in many fields of
gastroenterology and hepatology. The aim of this series is to
highlight some of these topics that deserve particular interest.
Research in the field of viral hepatitis has been very intense and
successful in recent years. The hepatitis B virus is one of the
best explored at the current level of virology. Not only the
nucleotid sequence of the viral DNA can be decoded, but also the
amino acid compounds of its genetic products are known today. Since
the techniques of molecular biology have increasingly found access
to clinical laboratory use, hepatitis B virus infection can serve
as an example for the importance of molecular biology in clinical
hepa tology. Another example for the interdependence of basic
science and clini cal medicine represents the research on bile acid
metabolism. The investigation of bile acids has revealed new
diagnostic approaches to hepatic and intestinal disorders.
Commercial kits for the routine measurement of serum bile acids in
clinical laboratories by enzymatic or radioimmunologic techniques
are now available. The diagnostic value of these measurements in
gastroenterology and hepatology shall be defined. Another aspect of
bile acid research leads to new per spectives in the treatment of
gallstone disease. The dissolution of cholesterol gallstones by
chenodeoxycholic acid (therapy) may be quoted as the best example
for the development of new phar macotherapeutic principles derived
from basic bile acid research."
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