Oxidative Stress in Aging: From Model Systems to Human Diseases
discusses the role of free radicals in aging in different animal
models, as well as the relevance of free radicals on age-related
diseases and pathological conditions in humans (following an
introduction section of the basics and theory of free radicals).
Human aging is a complex phenomenon - not everyone gets the same
diseases and dies from the same cause. Accumulating reports
implicate the connection between free radicals and various diseases
and age-related pathological conditions. Although the causal
relationships have not been established, it is necessary to discuss
how free radicals are involved in each situation. In addition, the
major interventions trials of antioxidant supplements in
age-related disease, cancer and so forth are reviewed and
discussed.
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