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Leukemias - Principles and Practice of Therapy (Hardcover, New)
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Leukemias - Principles and Practice of Therapy (Hardcover, New)
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Edited by experts from one of the world's largest leukemia centers,
this book provides information on the biology of the variety of
leukemic disorders, up-to-date diagnostic testing and many new
developments in therapy. Chapters covering new treatments present
an outlook for the future and explain the rationale for ongoing
clinical trials. Topics include: * Targeted therapy, e.g. tyrosine
kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors,
BCR-ABL inhibitors) * Ras inhibitors * Epigenetic therapy
(hypomethylaters and histone deacetylase inhibitors) * Lenalidomide
analogs * New chemotherapy drugs, e.g. clofarabine, cloretazine,
sapacitabine, forodesine * Combinations of chemotherapy with kinase
inhibitors (e.g. ALL induction protocols in combination with
dasatinib or imatinib) * New monoclonal antibodies (lumiliximab,
humaxCD20, anti-CD40) * Thrombopoietic agents Leukemias: Principles
and Practice of Therapy * Includes practical information to guide
you in challenging situations, such as treatment of elderly
patients, pregnancy, relapsed and refractory disease * Incorporates
chapters on supportive care and pharmacologic information about the
most frequently used drugs in this area
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