Structure-Based Drug Design (Hardcover)

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

General

Imprint:	Routledge Member of the Taylor and Francis Group
Country of origin:	United States
Release date:	July 1997
First published:	2008
Editors:	Pandi Veerapandian
Dimensions:	234 x 156 x 41mm (L x W x T)
Format:	Hardcover
Pages:	664
ISBN-13:	978-0-8247-9869-7
Categories:	Books > Science & Mathematics > Chemistry > Crystallography Books > Medicine > Other branches of medicine > Pharmacology > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Books > Science & Mathematics > Chemistry > Analytical chemistry > Qualitative analytical chemistry > Magnetic resonance
LSN:	0-8247-9869-4
Barcode:	9780824798697

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