Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Genomes 4 (Paperback, 4th edition)
Loot Price: R1,916
Discovery Miles 19 160
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Genomes 4 (Paperback, 4th edition)
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Genomes 4 has been completely revised and updated. It is a
thoroughly modern textbook about genomes and how they are
investigated. As with Genomes 3, techniques come first, then genome
anatomies, followed by genome function, and finally genome
evolution. The genomes of all types of organism are covered:
viruses, bacteria, fungi, plants, and animals including humans and
other hominids. Genome sequencing and assembly methods have been
thoroughly revised including a survey of four genome projects:
human, Neanderthal, giant panda, and barley. Coverage of genome
annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9
and GWAS methods of determining gene function covered. The
knowledge gained from these techniques forms the basis of the three
chapters that describe the three main types of genomes: eukaryotic,
prokaryotic (including eukaryotic organelles), and viral (including
mobile genetic elements). Coverage of genome expression and
replication is truly genomic, concentrating on the genome-wide
implications of DNA packaging, epigenome modifications, DNA-binding
proteins, non-coding RNAs, regulatory genome sequences, and
protein-protein interactions. Also included are applications of
transcriptome analysis, metabolomics, and systems biology. The
final chapter is on genome evolution, focusing on the evolution of
the epigenome, using genomics to study human evolution, and using
population genomics to advance plant breeding. Established methods
of molecular biology are included if they are still relevant today
and there is always an explanation as to why the method is still
important. Each chapter has a set of short-answer questions,
in-depth problems, and annotated further reading. There is also an
extensive glossary. Genomes 4 is the ideal text for upper level
courses focused on genomes and genomics.
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