This text encompass an up-to-date, comprehensive review of the
state-of-the-art for gland preserving therapies. Fully updated and
revised, this text evaluates the scientific evidence for the
evolving trend to treat intermediate risk, clinically localized
prostate cancer in a focally ablative manner with novel
gland-preserving, focal therapy methods. Various ablative devices
such as high intensity focused ultrasound, irreversible
electroporation, photodynamic therapy, cryotherapy and laser
ablation, among others, is discussed in regard to their strengths
and limitations as a therapeutic modality. Emphasis is placed on
patient selection and outcomes utilizing both advanced imaging
techniques and pathologic evaluation. Current and new approaches to
image cancer foci within the prostate (multiparametric
ultrasonography, multiparametric magnetic resonance image, etc) are
presented along with various biopsy techniques, including robotics
to map prostate cancer. Patient selection based on imaging and
genomic classification, adjuvants to enhance therapy, treatment
strategy, outcomes and patient centered concerns is discussed,
providing an acceptable balance between cancer control and improved
quality of life for patients. Written by experts in the field and
lavishly illustrated with detailed line-art and photographs,
Imaging and Focal Therapy of Early Prostate Cancer, Second Edition
is designed as a comprehensive resource for urologists, radiation
oncologists, medical oncologists, radiologists, uropathologists,
molecular biologists, biomedical engineers, other clinicians --
residents, fellows, nurses and allied professionals -- and
researchers with an interest in the diagnosis and novel treatment
of prostate cancer. It will provide insight into the latest
research and clinical applications of image-guided diagnosis and
minimally invasive focal, gland-preserving treatment for prostate
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