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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA

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RNA Exosome (Hardcover, 2010 ed.) Loot Price: R1,194
Discovery Miles 11 940
You Save: R3,446 (74%)
RNA Exosome (Hardcover, 2010 ed.): Torben Heick Jensen

RNA Exosome (Hardcover, 2010 ed.)

Torben Heick Jensen

Series: Advances in Experimental Medicine and Biology, 702

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List price R4,640 Loot Price R1,194 Discovery Miles 11 940 | Repayment Terms: R112 pm x 12* You Save R3,446 (74%)

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The diversity of RNAs inside living cells is amazing. We have known of the more "classic" RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3'end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Series: Advances in Experimental Medicine and Biology, 702
Release date: December 2010
First published: 2010
Editors: Torben Heick Jensen
Dimensions: 254 x 178 x 8mm (L x W x T)
Format: Hardcover
Pages: 144
Edition: 2010 ed.
ISBN-13: 978-1-4419-7840-0
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Cellular physiology
Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA
LSN: 1-4419-7840-2
Barcode: 9781441978400

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