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Books > Medicine > Clinical & internal medicine > Haematology
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Small Molecules in Hematology (Paperback, Softcover reprint of the original 3rd ed. 2018)
Loot Price: R2,592
Discovery Miles 25 920
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Small Molecules in Hematology (Paperback, Softcover reprint of the original 3rd ed. 2018)
Series: Recent Results in Cancer Research, 212
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This book, written by respected experts, discusses in detail the
latest developments in targeted therapy for hematologic
malignancies using small molecules. It covers a wide range of small
molecules including tyrosine kinase inhibitors, immunomodulatory
drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor
venetoclax, and the proteasome inhibitor carfilzomib. For each
molecule, aspects such as the chemical structure, mechanism of
action, drug targets, drug interactions, preclinical studies,
clinical trials, treatment applications, and toxicity are
discussed. Extensive research into the molecular mechanisms of
cancer has heralded a new age of targeted therapy. The field of
precision cancer therapy is now growing rapidly, and the advances
being made will mean significant changes in the treatment
algorithms for cancer patients. Numerous novel targets that are
crucial for the survival of cancer cells can be attacked by small
molecules such as protein tyrosine kinase inhibitors. An
accompanying volume addresses the use of small molecules in
oncology, and the two volumes together represent the third edition
of the book originally published under the same title.
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