This title includes a number of Open Access chapters. This book
contains a selection of chapters aimed to provide a better
understanding prion structure and biology. Together these chapters
provide an overview of prion biology and underscore some of the
challenges we face if we want to understand how this lively
pathogen propagates and evolves in mammals. There is also mounting
evidence that studying prion biology has a wider relevance due to
similarities in the processes of protein misfolding and aggregation
between prion disorders and other neurodegenerative disorders such
as Alzheimer's, Parkinson's, and Huntington's diseases.
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