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Aptamers for Analytical Applications - Affinity Acquisition and Method Design (Hardcover)
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Aptamers for Analytical Applications - Affinity Acquisition and Method Design (Hardcover)
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An essential guide that puts the focus on method developments and
applications in aptamers In recent years, aptamer-based systems
have been developed for a wide-range of analytical and medical
applications. Aptamers for Analytical Applications offers an
introduction to the topic, outlines the common protocols for
aptamer synthesis, as well as providing information on the
different optimization strategies that can obtain higher affinities
to target molecules. The contributors?noted experts on the
topic?provide an in-depth review of the characterization of
aptamer-target molecule interaction and immobilization strategies
and discuss the developments of methods for all the relevant
applications. The book outlines different schemes to efficiently
immobilize aptamers on substrates as well as summarizing the
characterization methods for aptamer-ligand complexes. In addition,
aptamer-based colorimetric, enzyme-linked, fluorescent,
electrochemical, lateral flow and non-labeling analytical methods
are presented. The book also reflects state-of-the-art and emerging
applications of aptamer-based methods. This important resource:
-Provides a guide to aptamers which provide highly specific and
sensitive molecular recognition, with affinities in the range of
antibodies and are much cheaper to produce -Offers a discussion of
the analytical method developments and improvements with
established systems and beyond -Offers a comprehensive guide to all
the relevant application areas -Presents an authoritative book from
contributors who are noted experts in the field Written for
analytical chemists, biochemists, analytical researchers, Aptamers
for Analytical Applications is a comprehensive book that adopts a
methodological point of view to the important aspects of aptamer
generation and modification with a strong emphasis on method
developments for relevant applications.
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