Carbohydrate-Based Vaccines and Immunotherapies (Hardcover)

The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. "Carbohydrate-Based Vaccines and Immunotherapies" comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments.

With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances.

Key topics covered by "Carbohydrate-Based Vaccines and Immunotherapies" include:

Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi

Using adjuvants to improve immunogenicity and/or immunological properties of vaccines

Choosing and designing proper adjuvants for specific targets

Abnormal carbohydrates expressed by tumors

Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy

Clinical trials results for synthetic cancer vaccines

Glycoengineering of cell surface carborhydrates and its anticancer applications

Using cell surface carbohydrates for disease diagnosis

A single, convenient source of state-of-the-art information from leading authorities in the field, "Carbohydrate-Based Vaccines and Immunotherapies" is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.

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