A must-have book for systems analysts, architects and managers interested in enhancing successful communication in their organisation.* Provides detailed examples of how to understand and implement 'fundamental modeling concepts' for IT-systems communication* Provides an already successfully implemented model that has been used at: Siemens, Alcatel, SAP and others* Benefits from extensive theoretical and practical research* Provides guidelines on how 'fundamental modeling concepts' can be used to support UML, OO, MDA and Architectural Patterns

Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology.

These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to development to cardiology. The book contains a dozen chapters written by world experts on these topics, half focusing on the optogenetic molecular tools themselves, and half on the genetic and hardware approaches that make them powerfully useful in intact tissues and organisms.
Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist