Edited by premier researchers in the field, this is a unique book that comprehensively covers the important topic of uterine leiomyomas from biology, health disparity challenges, impact on fertility, novel risk factors, imaging as well as innovative minimally-invasive to non-invasive treatment options with over eleven chapters by leading practitioners and medical investigators of this disease. Although all areas of uterine leiomyoma are reviewed and updated, with a focus on the medical treatment of this common condition, which offers promise to millions of patients with symptomatic uterine leiomyoma. This book describes important facets of this disease such as the role of vitamin D deficiency as a novel risk factor and its higher incidence in women of color. Novel approaches for treatment using green tea extract or radiofrequency volumetric thermal ablation are also described in detail. This book is essential reading for gynecologists, family doctors, physician assistants, nurse practitioners, medical students, OB/GYN residents and fellows, reproductive biologists, as well as other health care providers who care for women with this common disease.