Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound�) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial.

Amusement is an emotion with power. It has the power to make us laugh, but it can also have a power over us (for good or for ill) to control our attention or memory. Amusement can empower our resistance to oppression, or it can itself become an oppressive force. Our amusement can make others feel shame. Amusement even has the power to affect (and be affected by) out moral assessment of others. This volume offers twelve essays from leading and emerging scholars that explore the moral quagmire that is the emotion of amusement. It is a collection that considers the moral psychology of amusement from a range of perspectives, going as far back as ancient Chinese and Greek philosophy up to the most current psychological and sociological findings.

This book introduces an approach to active system control design and development to improve the properties of our technological systems. It extends concepts of control and data accumulation by explaining how the system model should be organized to improve the properties of the system under consideration. The authors define these properties as reliability, performance and energy-efficiency, and self-adaption. They describe how they bridge the gap between data accumulation and analysis in terms of interpolation with the real physical models when data used for interpretation of the system conditions. The authors introduce a principle of active system control and safety - an approach that explains what a model of a system should have, making computer systems more efficient, a crucial new concern in application domains such as safety critical, embedded and low-power autonomous systems like transport, healthcare, and other dynamic systems with moving substances and elements. On a theoretical level, this book further extends the concept of fault tolerance, introducing a system level of design for improving overall efficiency. On a practical level it illustrates how active system approach might help our systems be self-evolving.

Walking Guides are a series that showcases the world's great cities, with this streamlined, itinerary-driven guide, created in a handy, take-along format.   The best way to appreciate the city is to walk: it is only on foot that you can explore the lively districts in all their variety and diversity. This volume offers 14 itineraries that will guide you step by step to the most hidden and picturesque corners of Paris. The "Whirlwind Tour" section includes ideas for visiting the entire city in one day or in a weekend, enjoying a solo trip or a family visit with children. The walks through the city, from the Tour Eiffel and Les Invalides to Place du Châtelet and Les Halles, touch on each of the points of interest on the map. The more detailed descriptions offer interesting information about the museums and other sites, including the Cathédrale de Notre-Dame de Paris, the Musée du Louvre, and the Arc de Triomphe. Decidedly Parisian, the guide introduces the reader to the more unusual aspects of the city's culture, such as haute couture, art, theatre, and the best of local life, from street markets to minor museums and visits to architectural peculiarities.

A complete illustrated picture walk thru guide on comic book digital inking using the popular freeware art program called Pixia. If you ever wondered what Pixia the freeware art program was, or how to use it, this book is for you. If you wanted a freeware program with same capabilities as Gimp or Photoshop for Windows users, that will allow you digital ink for your comic books, comic strips, or manga, then this book is for you.

Brian Robinson Sr., shares with us his erotic writings titled Warm Rainy Sensations...Urban Fiction love tales at its best Inside you will find three short stories, and they will keep you wanting more. Brian introduces to you Where She Wants to Be, SHY, and The Sadie Hawkins Surprise and you won't be disappointed. Especially the ladies.

A journey through life from early childhood in England to happy retirement in beautiful Nova Scotia, Canada, this memoir traces a man's milestones through interesting years. It spans World War II, the rapid and constant whirl of the emerging world of technology, an experience with the Cuban Missile Crisis, and many travels in which his growing spirituality emerged. Encounters with death and cancers are recalled together with the knowledge gained to cope with these and other adversities. It is a journey to be shared and may well help in discovering your own story.

The Financial Stability Oversight Council (FSOC) was created by the Dodd-Frank Act(DFA) in 2010 as part of a comprehensive reform of banking and securities market regulators. The council is charged with monitoring systemic risk in the financial system and coordinating several federal financial regulators. The FSOC is expected to facilitate communication among existing financial regulators intending to identify sources of financial instability that cross agency regulatory jurisdiction, or that reside in gaps in the financial regulatory framework. This book describes the mission, membership, and scope of the FSOC with its focus on establishing a framework for mitigating systemic risk.

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone

Leaving all to follow God's call is the story of an African American family whom God called to leave a secure and comfortable pastorate to serve as missionaries to Africa.