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Adult hydrocephalus is an insidious yet treatable condition that
develops slowly, with usual onset around 60 years of age. It is
poorly recognized and many cases are not diagnosed until late in
the course of disease, leading to poorer patient outcomes and a
high financial cost to healthcare providers. The resulting
neurological symptoms include gait/balance problems, loss of
bladder control, and a cognitive decline leading to dementia, which
is often mistaken for Alzheimer's disease. This book - the first
published on this topic since 1993 - provides comprehensive
guidelines to improve the speed and accuracy of diagnosis, and
covers various neurosurgical techniques used to treat the disease,
including the insertion of different types of shunts and endoscopic
third ventriculostomy. This is essential reading for neurologists,
neurosurgeons, family physicians, and radiologists who may well
encounter adult patients with hydrocephalus more often than they
realize.
Questions regarding the nature and appropriate management of
cavernous malformation (CM) have clouded researchers and those
faced with making clinical decisions for several decades. CMs may
be seen as an incidental finding on MRI studies, or they may
present with symptoms, such as seizures or intracranial hemorrhage,
often causing severe neurologic deficit. Cavernous Malformations of
the Nervous System provides a comprehensive and authoritative
review of the current practice in diagnosis and management of these
cerebrovascular disorders. Emphasis has been laid on the
understanding of basic sciences with chapters committed to
understanding of CCM1, 2 and 3 genes and their role in CCM biology,
as well as clinical genetics. Controversial topics which continue
to pose treatment challenges such as safety of anticoagulation and
prophylactic management during pregnancy are also discussed. This
book will be of interest to basic science researchers,
neurosurgeons and vascular neurologists both in academic
institutions and private practice.
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