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Heart Failure Management: The Neural Pathways (Hardcover, 1st ed. 2016): Edoardo Gronda, Emilio Vanoli, Alexandru Costea Heart Failure Management: The Neural Pathways (Hardcover, 1st ed. 2016)
Edoardo Gronda, Emilio Vanoli, Alexandru Costea
R3,275 R2,738 Discovery Miles 27 380 Save R537 (16%) Ships in 10 - 15 working days

This book describes the most recent insights into heart failure and the role played by autonomic nervous system pathophysiology in it, discussing the therapeutic implications. While current therapeutic approaches are able to control the effects of excessive adrenergic activation in heart failure syndrome, the underlying abnormalities of adrenergic control remain unaltered and can still cause progression to unmanageable end-stage heart failure. New therapeutic pathways are therefore being explored with a view to developing interventions that can directly modulate adrenergic over-activity and restore a more appropriate balance in neural control of the cardiovascular system. The book opens by examining current heart failure therapies. Advances in our understanding of autonomic regulation/dysregulation in heart failure are then discussed in detail, in the context of the search for more effective therapies. A concluding section addresses the role of autonomic nervous system denervation in heart failure. The authors are top scientists from leading research centers.

Brain and Heart Dynamics (Hardcover, 1st ed. 2020): Stefano Govoni, Pierluigi Politi, Emilio Vanoli Brain and Heart Dynamics (Hardcover, 1st ed. 2020)
Stefano Govoni, Pierluigi Politi, Emilio Vanoli
R14,580 Discovery Miles 145 800 Out of stock

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Brain and Heart Dynamics (Mixed media product, 1st ed. 2020): Stefano Govoni, Pierluigi Politi, Emilio Vanoli Brain and Heart Dynamics (Mixed media product, 1st ed. 2020)
Stefano Govoni, Pierluigi Politi, Emilio Vanoli
R20,615 Discovery Miles 206 150 Out of stock

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Heart Failure Management: The Neural Pathways (Paperback, Softcover reprint of the original 1st ed. 2016): Edoardo Gronda,... Heart Failure Management: The Neural Pathways (Paperback, Softcover reprint of the original 1st ed. 2016)
Edoardo Gronda, Emilio Vanoli, Alexandru Costea
R2,440 Discovery Miles 24 400 Out of stock

This book describes the most recent insights into heart failure and the role played by autonomic nervous system pathophysiology in it, discussing the therapeutic implications. While current therapeutic approaches are able to control the effects of excessive adrenergic activation in heart failure syndrome, the underlying abnormalities of adrenergic control remain unaltered and can still cause progression to unmanageable end-stage heart failure. New therapeutic pathways are therefore being explored with a view to developing interventions that can directly modulate adrenergic over-activity and restore a more appropriate balance in neural control of the cardiovascular system. The book opens by examining current heart failure therapies. Advances in our understanding of autonomic regulation/dysregulation in heart failure are then discussed in detail, in the context of the search for more effective therapies. A concluding section addresses the role of autonomic nervous system denervation in heart failure. The authors are top scientists from leading research centers.

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