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Local treatment cures about 30 to 40% of cancers, this proportion
depending on the follow-up required to establish it. This means
that 60 to 70% of the malignant neoplasias are disseminated either
perceptibly (leukemias, visible metas- tases) or imperceptibly,
forming a 'minimal imperceptible disease', which local treatment
leaves, whether it consists of surgery, radiotherapy, or surgery
plus radiotherapy. When the neoplastic tissue is voluminous enough
to be per- ceptible, cures can be obtained with chemotherapy or
chemo- immunotherapy. When the neoplastic disease is imperceptible,
made up of micrometastases, it apparently can be cured by systemic
postsurgical chemotherapy, immunotherapy, or chemoimmunotherapy.
Hence there is the need for intensive development of these medical
therapies which are applied by the medical oncol- ogist and, at
present, consist of chemotherapy, immuno- therapy, or
chemoimmunotherapy. These medical thera- peutics can only grow with
scientific development, the main weapon of which is experimental
and clinical pharmacology. These volumes report the communications
presented at the 1979 EORTC Annual Plenary Session on Cancer Chemo-
and Immunopharmacology.
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Sam Smith
CD
R383
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