Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.

This first such volume in this field, "Sleep Disorders: Diagnosis and Therapeutics" explores sleep pharmacology and therapeutics. This text is an introduction for clinicians and researchers who are new to sleep pharmacology and outlines the wider range of therapeutic options currently available to them. Leading researchers in the area of experimental and clinical and psychopharmacology critically assess the progress in their specialist fields.

For seasoned clinicians, the book assists in selecting the most appropriate methodologies and treatment options designed to circumvent the problems in combating sleep disorders. The use of this knowledge is essential for the development of skills and techniques in sleep disorders and their treatment and diagnosis.

"Sleep Disorders: Diagnosis and Therapeutics" not only informs, but also stimulates research in this area and is a must-have text for psychiatrists, psychopharmacologists, and experimental and clinical pharmacologists, psychologists, and neuroscientists. This resource is also appropriate for physicians and scientists from academic centers, commercial and clinical laboratories, and those who are involved in research and development of sleep pharmaceuticals.