This issue of Dermatologic Clinics, guest edited by Drs. Lauren Meshkov Bonati and Jared Jagdeo, is devoted to Lesbian, Gay, Bisexual, and Transgender Dermatology. Articles in this timely issue include: Historical Perspective on the Dermatologic Care of Sexual and Gender Minority Populations; Healthcare Inequities and Resultant Morbidity in the Sexual and Gender Minority Population; Editorial: Transgender Patients' Experiences in Healthcare; Medical Dermatology and Multidisciplinary Care for Lesbian, Gay, Bisexual, Transgender, and Questioning Patients; Skin Cancer and Risk Factors in the Lesbian, Gay, Bisexual, Transgender, and Questioning Population; Acne and the Lesbian, Gay, Bisexual, and Transgender Teenager; Penile, Scrotal, and Anal Dermatitides in Male Sexual and Gender Minority Patients; What Every Dermatologist Should Know About PrE P; Where Do We Stand Now? A Survey of Physicians Involved in Gender Affirming Care; Androgenetic Alopecia in Gender Minority Patients; Minimally Invasive Procedures for Gender Affirmation; Surgical Facial Aesthetics for Gender Affirmation; Ways to Improve Sexual and Gender Minority Care in the Office and Institution; and How to Start a Resident Clinic for Lesbian, Gay, Bisexual, and Transgender Patients.