The recent introduction of nanomedicines in the drug therapy arena is revolutionizing the management of severe diseases. The key advance in the field is the optimization of the biological fate of drug molecules, thus improving the therapeutic effect while keeping to a very minimum the associated toxicity. Volume one of this book series, Nanoplatforms in Drug Delivery, established the basic aspects in the development of drug-loaded nanoplatforms, the so-called nanomedicines or nanodrugs, focusing on representative materials and strategies used in their formulation. Taking advantage of the advanced conceptualizations on nanomedicine engineering that were described in volume one, volume two, Nano-Engineering Strategies and Nanomedicines against Severe Diseases, analyzes in depth special features related to the formulation of nanoplatforms for oral, dental, topical and transdermal, pulmonary and nasal, ocular and otic, vaginal, and brain drug delivery and targeting. Particular aspects of nanomedicine engineering and in vivo fate associated with the routing of drug administration are given special attention. In addition, an up-to-date view is presented on the use of nanomedicines against severe diseases, such as cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, and metabolic diseases. The chapters analyze the key factors that need to be controlled to achieve the optimum therapeutic effect. Attention is further given to gene delivery and the recent concept of nanotheranosis.

Forage crops include several species of grasses and legumes that are widely used as animal fodder in the form of hay, pasturage and silage, as well as for turf and erosion control. Some forage grasses are also being considered for bio-energy generation. In this book leading researchers review the latest advances in molecular genetics and genomics; they also examine the success of breeding programs for forage grasses and legume species. The book will be useful for students and young researchers with an interest in forage, turf and bio-energy crops improvements.

Magnetic colloids are very promising stimuli-sensitive materials for drug delivery because of their magnetic field responsiveness. An applied magnetic field can concentrate the magnetic nanodevice at the desired site, keeping it there until the drug is totally released. Furthermore, the versatility of magnetic colloids allows the design of multifunctional nanoplatforms with combined therapy and imaging functionalities against diseases with high morbidity. This book summarises the most important advances in the formulation and functionalisation of such magnetic micro- and nano-particles, and also describes the recent advances on their use in biomedicine.

The recent introduction of nanomedicines in the drug therapy arena is revolutionizing the management of severe diseases. The key advance in the field is the optimization of the biological fate of drug molecules, thus improving the therapeutic effect while keeping to a very minimum the associated toxicity. Volume one of this book series, "Nanoplatforms in Drug Delivery," established the basic aspects in the development of drug-loaded nanoplatforms, the so-called nanomedicines or nanodrugs, focusing on representative materials and strategies used in their formulation.

Taking advantage of the advanced conceptualizations on nanomedicine engineering that were described in volume one, volume two, Nano-Engineering Strategies and Nanomedicines against Severe Diseases, analyzes in depth special features related to the formulation of nanoplatforms for oral, dental, topical and transdermal, pulmonary and nasal, ocular and otic, vaginal, and brain drug delivery and targeting. Particular aspects of nanomedicine engineering and "in vivo" fate associated with the routing of drug administration are given special attention. In addition, an up-to-date view is presented on the use of nanomedicines against severe diseases, such as cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, and metabolic diseases. The chapters analyze the key factors that need to be controlled to achieve the optimum therapeutic effect. Attention is further given to gene delivery and the recent concept of nanotheranosis.