This important book is to present the reader with developments concerning glutathione research. This work focuses on the synthesis-degradation and oxidation-reduction cycles of glutathione, the physiological functions of glutathione (especially in mammalian cells), and the analytical methods used to accurately measure the glutathione status of cells. This resource addresses specific modification of glutathione metabolism that is of special interest in the treatment of some tumors. This rare volume also introduces some different, new techniques on how to accurately measure glutathione, specifically in its oxidized form. Anyone involved with biochemistry, physiology, toxicology, pharmacology, nutrition and radiation biology will find this publication interesting and filled with useful information. It is also a valuable reference for research scientists in such fields as aging, metabolism disorders, and glutathione research.

The aim of this important book is to present the reader with developments concerning glutathione research. This work focuses on the synthesis-degradation and oxidation-reduction cycles of glutathione, the physiological functions of glutathione (especially in mammalian cells), and the analytical methods used to accurately measure the glutathione status of cells. This resource addresses specific modification of glutathione metabolism that is of special interest in the treatment of some tumors. This rare volume also introduces some different, new techniques on how to accurately measure glutathione, specifically in its oxidized form. Anyone involved with biochemistry, physiology, toxicology, pharmacology, nutrition and radiation biology will find this publication interesting and filled with useful information. It is also a valuable reference for research scientists in such fields as aging, metabolism disorders, and glutathione research.

"In Vitro" Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating "in vitro" organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular "in vitro" models for toxicology and pharmacology studies.
Key Features
* Meets the continuing demand for information in this field
* Compares "In Vitro" techniques with other methods
* Describes cell-culture methods used to investigate toxicity in cells derived from different organs
* Includes contributions by leading experts in the field