The Second World War affected the lives and shaped the experience of millions of individuals in Germany--soldiers at the front, women, children and the elderly sheltering in cellars, slave laborers toiling in factories, and concentration-camp prisoners and POWs clearing rubble in the Reich's devastated cities.
Taking a "history from below" approach, the volume examines how the minds and behaviour of individuals were moulded by the Party as the Reich took the road to Total War. The ever-increasing numbers of German workers conscripted into the Wehrmacht were replaced with forced foreign workers and slave labourers and concentration camp prisoners. The interaction in everyday life between German civilian society and these coerced groups is explored, as is that society's relationship to the Holocaust.
From early 1943, the war on the home front was increasingly dominated by attack from the air. The role of the Party, administration, police, and courts in providing for the vast numbers of those rendered homeless, in bolstering civilian morale with "miracle revenge weapons" propaganda, and in maintaining order in a society in disintegration is reviewed in detail.
For society in uniform, the war in the east was one of ideology and annihilation, with intensified indoctrination of the troops after Stalingrad. The social profile of this army is analysed through study of a typical infantry division. The volume concludes with an account of the various forms of resistance to Hitler's regime, in society and the military, culminating in the failed attempt on his life in July 1944.

This book focuses on broadly defined areas of chemical information science- with special emphasis on chemical informatics- and computer-aided molecular design. The computational and cheminformatics methods discussed, and their application to drug discovery, are essential for sustaining a viable drug development pipeline. It is increasingly challenging to identify new chemical entities and the amount of money and time invested in research to develop a new drug has greatly increased over the past 50 years. The average time to take a drug from clinical testing to approval is currently 7.2 years. Therefore, the need to develop predictive computational techniques to drive research more efficiently to identify compounds and molecules, which have the greatest likelihood of being developed into successful drugs for a target, is of great significance. New methods such as high throughput screening (HTS) and techniques for the computational analysis of hits have contributed to improvements in drug discovery efficiency. The SARMs developed by Jurgen and colleagues have enabled display of SAR data in a more transparent scaffold/functional SAR table. There are many tools and databases available for use in applied drug discovery techniques based on polypharmacology. The cheminformatics approaches and methodologies presented in this volume and at the Skolnik Award Symposium will pave the way for improved efficiency in drug discovery. The lectures and the chapters also reflect the various aspects of scientific enquiry and research interests of the 2015 Herman Skolnik award recipient.

6-10 jaar/years. Kinders is mal oor Speurder Kwaaikofski! Uiteindelik kan hulle nóg ’n heerlike speuravontuur geniet. Kwaaikofski het kompetisie: ’n ander speurder krap in sy slaai! Hierdie ou noem homself ’Koning’ en is heeltemal te groot vir sy skoene. Kwaaikofski kan dit beslis nie daar los nie – hierdie dorp is te klein vir albei van hulle. ’n Speurkompetisie sal bewys wie nou eintlik die speurkoning is!

Kwaaikofski lê met 'n gebreekte been in die hospitaal. En boonop besteel 'n dief almal op die kindervloer. Kwaaikofski begin die saak ondersoek - al is sy been in gips. Hy maak Monty, die seun met wie hy 'n kamer deel, sy assistent. Monty kan oral rondloop, maar hy kan nie praat nie, want sy kakebeen is gebreek. Hierdie saak gaan 'n tameletjie wees, maar Kwaaikofski laat hom nie onderkry nie!

Kwaaikofski verwag net een ding van skool: rus en vrede! Dit is tog die enigste plek waar ’n besige privaat speurder kan ontspan. Maar nou moet hy ondersoeke in sy eie klas doen!

Die nuwe seun in die klas is in groot moeilikheid. Die oplossing is voor die hand liggend: Kwaaikofski lok die skuldiges in ’n onweerstaanbare soet lokval!

Kwaaikofski is ’n privaatspeurder. Hy het nou eenmaal ’n talent daarvoor. Gee hom ’n glas melk, Carpenters kougom en sy spesiale kep en hy is gereed vir enigiets! Hierdie omnibus bevat drie van Speurder Kwaaikofski se gewildste avonture vir beginnerlesers. Hierdie keer krap ’n ander speurder krap in sy slaai, hy moet uitvind wie Olga se luukse motor beskadig het en hy beland boonop in die kollig op die verhoog . . .

Kwaaikofski is ’n privaatspeurder. Hy het nou eenmaal ’n talent daarvoor. Gee hom ’n glas melk, Carpenters kougom en sy spesiale kep en hy is gereed vir enigiets! Hierdie omnibus bevat drie van Speurder Kwaaikofski se gewildste avonture vir beginnerlesers. Kwaaikofski word deur ouens met kaalgeskeerde blou koppe ontvoer, hy vertel hoe sy pad vir die eerste keer met die van die Slang gekruis het en hy moet 'n vermiste hond opspoor.

Kwaaikofski is al ’n privaatspeurder vandat hy kan onthou. Selfs as ’n baba het hy elke boublokkie weer gekry, en ook elke lekker wat iewers in die sandput verdwyn het. Hy het nou eenmaal ’n talent daarvoor. Gee hom ’n glas melk, Carpenters kougom en sy spesiale kep – wat sorg dat sy brein altyd teen die optimale temperatuur funksioneer – en hy is gereed vir enigiets! Hierdie omnibusuitgawe bevat drie van Speurder Kwaaikofski se gewildste avonture vir beginnerlesers. Kwaaikofski moet uitvind waarom sy gunsteling-kougom uit Olga se winkel verdwyn, die geheim van ’n vlieënde blou rubberkoei ontrafel en 'n vreemde pienk spook op die skoolgronde vastrek.

This Handbook expertly explores the profound transformations in international relations (IR) in recent decades. Proliferating cross-border challenges, including global financial crises, climate change, environmental degradation, irregular migration, and COVID-19, require governance structures that transcend the nation state and take both global and regional interplay, as well as problem-solving capacities, into account. Contributing authors investigate the effectiveness of international cooperation and performance in a diverse range of policy fields. Offering a comprehensive overview of the latest theoretical and empirical research on the interactions between global and regional governance, this book explicitly takes into account the rise of new powers and the Global South. It seeks to integrate perspectives, ideas and policies from both Western and non-Western societies in order to better explain relationships among multiplying actors in a highly interdependent world. This cutting-edge Handbook will be an essential read for academics and students of political science, IR, and related disciplines. Professionals in diplomatic, developmental, environmental, trade, and financial fields will also benefit from its accessible evaluation of global and regional governance.

Uiteindelik het Kwaaikofski sy eie rekenaar. Nou hoef hy nie meer sy speursake soos 'n speurder in die Middeleeue op te los nie! En dit is ook nie 'n minuut te laat nie, want Kwaaikofski se nuutste saak lei hom op 'n geheimsinnige dwaalspoor tot diep in die vreemde wereld van kuberkrakers. Hy moet 'n geheimsinnige rekenaarspeletjie genaamd Towertuin opspoor, voor dit dalk te laat is...