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Fungal pathogens pose an on-going and serious threat for
poikilotherms and homeotherms, and can cause a broad spectrum of
diseases ranging from innocuous to life-threatening. In addition,
long-term exposure to some mycotoxigenic moulds can lead to
mycotoxicoses in human and animals. Given the expanding population
of immune compromised hosts, the list of fungal opportunists grows
longer every year. Moreover, antifungal resistance, drug-related
toxicity and our limited arsenal of antifungals have exacerbated
the situation. To address these problems, strategies such as the
identification of novel targets, use of the structure-activity
relationship in rational drug design, development of new
formulations, modification of existing antifungals to combat
resistance, and bioavailability enhancement are called for. For the
reader's convenience, this book has been divided into three
sections. The first six chapters of Section I provide a timely
review of mycoses, from endemic to cosmopolitan and from
generalized to specific, while both chapters of Section II focus on
risks associated with mycotoxins. In closing, the two chapters of
Section III describe potential antifungal leads and drug candidates
based on phytochemicals and coumarin scaffold.
This book presents a comprehensive view on mycotoxins of
agricultural as well as non-agricultural environments and their
health effects in humans and animals. Mycotoxins have
immunosuppressive effects; but some of them can cause cancers,
mutagenicity, neurotoxicity, liver and kidney damage, birth
defects, DNA damage and respiratory disorders. The problem of
mycotoxins is long-lasting and their direct or indirect exposures
to humans and animals must be further discussed. The first chapter
will cover the historical perspective of mycotoxins along with
timeline while the second one will provide overview including
classification of mycotoxins and mycotoxicoses. The comprehensive
information/ literature on traditional, emerging and mushroom
mycotoxins will be given in chapters 3, 4 and 5 respectively.
Chapter 6 will deal with mycotoxins co-occurrence poisoning whereas
new and masked mycotoxins will be described in chapter 7. The
important aspects of mycotoxin studies like extraction,
characterization and analysis and management strategies will be
summarized in 8 and 9 chapters. The last chapter of the book will
cover the recent developments in toxicokinetic studies of
mycotoxins. The book will have the most up-to-date information and
recent discoveries to deliver accurate data and to illustrate
essential points to a wide range of readers including mycologists,
clinicians, agricultural scientists, chemists, veterinarians,
environmentalists and food scientists.
Fungal pathogens pose an on-going and serious threat for
poikilotherms and homeotherms, and can cause a broad spectrum of
diseases ranging from innocuous to life-threatening. In addition,
long-term exposure to some mycotoxigenic moulds can lead to
mycotoxicoses in human and animals. Given the expanding population
of immune compromised hosts, the list of fungal opportunists grows
longer every year. Moreover, antifungal resistance, drug-related
toxicity and our limited arsenal of antifungals have exacerbated
the situation. To address these problems, strategies such as the
identification of novel targets, use of the structure-activity
relationship in rational drug design, development of new
formulations, modification of existing antifungals to combat
resistance, and bioavailability enhancement are called for. For the
reader's convenience, this book has been divided into three
sections. The first six chapters of Section I provide a timely
review of mycoses, from endemic to cosmopolitan and from
generalized to specific, while both chapters of Section II focus on
risks associated with mycotoxins. In closing, the two chapters of
Section III describe potential antifungal leads and drug candidates
based on phytochemicals and coumarin scaffold.
This book presents a comprehensive view on mycotoxins of
agricultural as well as non-agricultural environments and their
health effects in humans and animals. Mycotoxins have
immunosuppressive effects; but some of them can cause cancers,
mutagenicity, neurotoxicity, liver and kidney damage, birth
defects, DNA damage and respiratory disorders. The problem of
mycotoxins is long-lasting and their direct or indirect exposures
to humans and animals must be further discussed. The first chapter
will cover the historical perspective of mycotoxins along with
timeline while the second one will provide overview including
classification of mycotoxins and mycotoxicoses. The comprehensive
information/ literature on traditional, emerging and mushroom
mycotoxins will be given in chapters 3, 4 and 5 respectively.
Chapter 6 will deal with mycotoxins co-occurrence poisoning whereas
new and masked mycotoxins will be described in chapter 7. The
important aspects of mycotoxin studies like extraction,
characterization and analysis and management strategies will be
summarized in 8 and 9 chapters. The last chapter of the book
will cover the recent developments in toxicokinetic studies of
mycotoxins. The book will have the most up-to-date
information and recent discoveries to deliver accurate data and to
illustrate essential points to a wide range of readers including
mycologists, clinicians, agricultural scientists, chemists,
veterinarians, environmentalists and food scientists.
This book discusses one of the biggest challenges of the food
industry, which is waste management. Food industries generate high
amounts of waste, both solid and liquid, resulting from the
production, processing and consumption of food. Stringent
environmental legislators have made the task of waste management
more challenging. Through the three sections of this book, the
readers are introduced to the different types of wastes generated,
utilization of waste through food processing industry and
sustainable waste management technologies. The different chapters
describe how the biomass and the valuable nutrients from food
industry wastes could be used to develop value-added products. The
book reiterates that food wastes and their by-products are an
excellent source of sugars, minerals, dietary fiber, organic acids,
bio active compounds such as polyphenols, carotenoids and
phytochemicals etc. This book is an excellent resource for industry
experts, researchers and students in the field of food science,
food processing and food waste management.
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