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Transdermal drug delivery systems are adhesive, dug containing
devices of defined surface area that deliver a pre-determined
amount of drug to the surface of intact skin at a pre-programmed
rate. These systems provide drug systemically at a predictable rate
and maintain the rate for extended periods of time. In this work an
attempt was made to formulate and evaluate TDDS for sustained
release Atorvastatin calcium by solvent casting method. Low
molecular weight, good permeability of Atorvastatin calcium made it
a suitable drug candidate for the development of transdermal
patches. The main objective of formulating the transdermal system
was to prolong the drug release time, reduce the frequency of
administration and to improve patient compliance. We sincerely hope
that this book will helpful to student as well as industry and
academic professionals involved in pharmaceutical and other related
science.
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