In many applications of econometrics and economics, a large proportion of the questions of interest are identification. An economist may be interested in uncovering the true signal when the data could be very noisy, such as time-series spurious regression and weak instruments problems, to name a few. In this book, High-Dimensional Econometrics and Identification, we illustrate the true signal and, hence, identification can be recovered even with noisy data in high-dimensional data, e.g., large panels. High-dimensional data in econometrics is the rule rather than the exception. One of the tools to analyze large, high-dimensional data is the panel data model.High-Dimensional Econometrics and Identification grew out of research work on the identification and high-dimensional econometrics that we have collaborated on over the years, and it aims to provide an up-todate presentation of the issues of identification and high-dimensional econometrics, as well as insights into the use of these results in empirical studies. This book is designed for high-level graduate courses in econometrics and statistics, as well as used as a reference for researchers.

The book presents a machine-generated literature review on CRISPR (clustered regularly interspaced short palindromic repeats) from 114 selected papers published by Springer Nature in the last few years, which are then organized by the book editors with a human-written introduction to each chapter. Each chapter presents summaries of predefined themes and provides the reader with a basis for further exploration of the topic. As one of the experimental projects initiated by Springer Nature for AI book content generation, this book shows the latest developments in the CRISPR field. It will be a useful reference for graduate students who are interested in CRISPR-related research and early-career researchers who need an overview of the current development of the field.

Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area.

This book presents basic design theories and principles and provides detailed analysis for excavation failure cases based on the author's research experience, aiming to provide a comprehensive picture of the subject matter. It focuses on the basal heave stability analysis, the apparent earth pressure as well as the strut force determination, the retaining wall deflection, the ground settlement, the protection measures such as jet grouting slabs or piles, case reports, back analysis methodology. From the very basic to the most advanced, it tries to attain theoretical rigorousness and consistency. On the other hand, this book also tries to cope with design practice, implemented by the recent publications from the authors. Students, researchers, and design engineers working in the field of civil engineering could benefit from this book.

This book presents basic design theories and principles and provides detailed analysis for excavation failure cases based on the author's research experience, aiming to provide a comprehensive picture of the subject matter. It focuses on the basal heave stability analysis, the apparent earth pressure as well as the strut force determination, the retaining wall deflection, the ground settlement, the protection measures such as jet grouting slabs or piles, case reports, back analysis methodology. From the very basic to the most advanced, it tries to attain theoretical rigorousness and consistency. On the other hand, this book also tries to cope with design practice, implemented by the recent publications from the authors. Students, researchers, and design engineers working in the field of civil engineering could benefit from this book.