This book is a collection of multidisciplinary papers presented at the Department of Physics of Milan University's congress on 28 and 29 June 2017, which was also intended as a kick-off meeting for the design of a novel science campus at the Expo site in Milan. The congress presented a snapshot of the department's research to the academic community, the media, policymakers and authorities as well as the public at large, and also provided an opportunity to strengthen interdisciplinary collaborations between the members of the department and other communities. This book is a valuable resource for scientists looking for synergetic projects, policymakers wanting to grasp scientists' points of view and for prospective graduate students seeking expanding areas of research.