This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Miriam Segal, will cover the important topic of Muscle Overactivity in Upper Motor Neuron Syndrome, including assessment and problem-solving for complex cases. Topics discussed in the volume will include: Functional/problem based assessment in patients with spinal cord injury; Special considerations in pediatric assessment; Special considerations and assessment of spasticity and multiple sclerosis; Pharmacologic treatment tools; Peripheral neurolysis; The role of physical and occupational therapy; Neurosurgical approaches; The neuro-orthopedic approach; Upper extremity problem-solving: Challenging cases; Lower extremity problem-solving: Challenging cases; and Emerging therapies.

Bryan Cranston stars in this crime drama based on US Customs official Robert Mazur's autobiography. The film follows Mazur (Cranston) as he goes undercover to infiltrate the money laundering operations of drug lord Pablo Escobar. Assuming the identity of successful businessman Bob Musella, Mazur promotes himself as the man who can turn dirty cash into clean. By laundering money for the drug cartels he hopes he will be led directly to the most powerful men at the top of the chain. In his new role as an undercover agent, Bob sets up complex networks of investments to protect the drug dealers' money and as he works his way up Escobar's organisation he is forced to go to new lengths to protect his cover and continue his mission. The cast also includes John Leguizamo, Benjamin Bratt and Diane Kruger.