The longing in Lucille's heart is as much a mystery to her as it is to those who love her. Even to those who wish to possess her. Only when she encounters a Cherokee cowboy riding on a buffalo, stolen from a Wild West show, does she feel a deep kinship and her mysterious longings are realized. Set in 1923 in rural Oklahoma, "Riding Buffaloes" is a perilous adventure awash in wildcat whiskey and unrequited desire. Lucille's devotion to following her heart takes her and her new husband, Earl Dean, to the brink of disaster. They contend with coarse cowboys, wild Indians, menacing gangsters, murderous moonshiners, and corrupt lawmen. Cloaked in cigarette smoke, soaked in moonshine, and crushed by infidelity, only luck, and her love for the buffalo can free Lucille.