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Features: • Includes computational approaches to study the
pharmacological properties of biomolecules in medicinal and
aromatic plants. • Details methods in ethnopharmacology including
chromatographical and analytical techniques. • Demonstrates
trends in sustainable use and management of medicinal and aromatic
plants. • Features information on databases and tools used in
computational phytochemistry for drug designing and discovery •
Elucidates the importance phytochemicals as immunomodulators in
herbal drug development including its nano-formulations.
Features: • Includes computational approaches to study the
pharmacological properties of biomolecules in medicinal and
aromatic plants. • Details methods in ethnopharmacology including
chromatographical and analytical techniques. • Demonstrates
trends in sustainable use and management of medicinal and aromatic
plants. • Features information on databases and tools used in
computational phytochemistry for drug designing and discovery •
Elucidates the importance phytochemicals as immunomodulators in
herbal drug development including its nano-formulations.
Manufacturing area with new equipment having high capacity compared
to previous one (Production Line) i.e. FBD, RMG, Co Mill and
Container Mixer. Manufacturing of Metformin ER 500mg tablets is
planned to do in new area with new equipment. As the size and
capacity of the equipments are bigger than previous equipments,
batch size of Metformin ER tablets is increasing from 0.4 mio to
0.6 mio. As the production in new area and new equipment,
qualification of area, equipment, water and air was carried out as
per qualification protocol. Now, further the process of
optimization was performed for Metformin ER tablets by identifying
the critical Process parameters i.e. standardization batch (BATCH
I). Before going to start process validation, one standardization
batch was taken, where the process optimization of critical
parameter like mixing speed, mixing time, lubrication time was
carried out; fast, 15 min, 15 min respectively the results for
that. Three process validation batches (PV-1, PV-2 and PV-3) of
commercial batch size were taken in which Manufacturing Process,
critical parameters, Validation status of equipments &
Validation criteria's were considered.
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