This issue details the latest knowledge of early diagnosis, risk factors, limited surgical treatments, and novel therapies for pancreatic diseases. Clinicians will learn the most prognostic scoring systems for acute pancreatitis, review the basics for early management of the disease, and see how current practice guidelines have evolved. Advances in radiological imaging when applied to the pancreas have resulted in enhanced staging and improved selection for surgical intervention. Endoscopy of the pancreas via both ERCP and endoscopic ultrasound has led to unprecedented access and potential for non-operative intervention. Pancreatic surgery now takes advantage of both minimally invasive approaches and techniques learned from organ transplantation. These latest advances are addressed in this issue by key opinion leaders.

Historically, agriculture has been crucial to Pakistan's economic growth and development and remains so even today. The sector employs almost half of the country's labor force, supplies key inputs to the country's manufacturing sector, generates a significant share of export earnings, and nourishes a rapidly growing population. Further, beyond agriculture is the wider rural economy, including nonfarm economic activities such as small enterprises, transport services, village retail shops, local schools, and clinics, all of which account for an estimated 40 to 57 percent of total rural household income. Given the importance of these rural activities, the slow growth of agriculture in recent years-averaging just 2.8 percent during the period 2010-2014-should be a source of concern for Pakistan. Can the country's agricultural sector and rural economy once again play a significant role in growth and development? Can it contribute to poverty reduction? Agriculture and the Rural Economy in Pakistan: Issues, Outlooks, and Policy Priorities seeks to answer these questions by examining the performance of both agriculture and the rural economy. The authors identify several measures that can promote agricultural productivity growth as well as wider economic and social development. These include increasing the efficiency of water use in the Indus river basin irrigation system, especially in the face of climate change; reforming policies and regulations that govern markets for agricultural inputs and commodities; and improving the provision of rural public services for health, education, women's empowerment, and community development. The analyses and conclusions in Agriculture and the Rural Economy in Pakistan will be of use to policy makers, development specialists, and others concerned with Pakistan's development. Contributors: Madiha Afzal, Nuzhat Ahmad, Faryal Ahmed, Mubarik Ali, Shujat Ali, Elena Briones Alonso, Hira Channa, Stephen Davies, Paul Dorosh, Gisselle Gajate Garrido, Arthur Gueneau, Madeeha Hameed, Brian Holtemeyer, Huma Khan, Katrina Kosec, Mehrab Malek, Sohail J. Malik, Shuaib Malik, Amina Mehmood, Dawit Mekonnen, Hina Nazli, Sara Rafi, Muhammad Ahsan Rana, Abdul Wajid Rana, Danielle Resnick, Khalid Riaz, Abdul Salam, Emily Schmidt, Asma Shahzad, David J. Spielman, James Thurlow, Ahmad Waqas, Edward Whitney, Fatima Zaidi.