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This volume explores sleep medicine, sleep science, and the sleep disorders that keep one-quarter of the U.S. population from getting this necessary component of normal cognitive functioning and survival.
With an emphasis on diagnostic techniques, particularly imaging, this handbook shines newfound attention on the genetic and clinical aspects of sleep medicine. Advances in basic science are explored, including a better understanding of sleep-wakefulness and new models of rapid eye movement (REM) sleep mechanisms. Advancements in the understanding of sleep-wake-dependent genes, gene products, and the role of sleep duration in mortality and morbidity are also presented, along with fascinating noninvasive neuroimaging studies that demonstrate marked changes in function during different sleep states.
Clinicians will gain new insights into the diagnosis of sleep
disorders and sleep science. In addition, researchers will have an
invaluable tool that will form a foundation for new approaches into
the ongoing study of sleep medicine.
Sleep and Movement Disorders is the second edition of a successful book that was the first of its kind. Since its publication in 2002, significant progress has been made in our understanding of motor control in sleep and the relationship between sleep and movement disorders. All three editors are authorities on the subject and have assembled expert specialists for their chapter authors. The topic is very timely, the latest edition of the International classification of sleep disorders (ICSD-2, 2005) included a separate category of 'Sleep Related Movement Disorders' emphasizing the increasing awareness of sleep-related movements and the importance of recognizing sleep-related movement disorders for diagnosis, differential diagnosis and treatment. This is a comprehensive resource, including all findings from the last 8 years of research. All the previous chapters have been revised with new materials and references. Several chapters have been added to address recent advances. For instance, new sleep-related disorders have been classified and diagnosed, including catathrenia, alternating leg muscle activation (ALMA), propriospinal myoclonus (PSM) at sleep onset, faciomandibular myoclonus at sleep onset, etc. Further understanding of the pathophysiology of RLS-PLMS is addresses, as is the neurobiology of REM Behavior Disorder (RBD), predictors of neurodegenerative diseases, and so on. Sleep and Movement Disorders is divided into four major sections and subsections preceded by an introductory essay to provide perspective on the subject. The book is intended for all sleep and movement disorders specialists as well as those neurologists, internists including pulmonologists, psychiatrists, psychologists, otolaryngologists, pediatricians, neurosurgeons, dentists and family physicians who must deal with the many patients suffering from undiagnosed or underdiagnosed sleep disorders including sleep-related abnormal movements.
Since the late 90 s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.
From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.
Practitioners will find invaluable research, information, and
laboratory techniques on such topics as sleep-wake-dependent genes,
the role of sleep duration in mortality and morbidity, and
advancements in the understanding of the neurobiology of sleep
disorders, including narcolepsy-cataplexy, restless legs syndrome,
REM behavior disorders, fatal familiar insomnia, sleep apnea and
heart failure, and nocturnal paroxysmal dystonia, amongst others.
In addition, significant advancements in therapies and drug
protocols are presented.
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