The extravasation of cytotoxic agents can result in severe local tissue damage and medical emergencies during tumour therapy. This revised compendium is intended to help clinicians assess any situation speedily and with certainty. The general section of the book includes topics such as predisposition, prevention, type of harm, general measures in handling extravasated drugs, specific antidotes, and documentation. In the 2nd edition, the scientific information contained in the general section and relating to the actual substances has been updated. The substance specific part of the book includes detailed instructions on handling more than 50 cytotoxic drugs, to initiate targeted measures. Templates for an extravasation set, overview tables, documentation sheets, and patient information, as we as a CD-ROM are included to support clinical practice. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic.

Paravasation von Zytostatika kann zu schwerwiegenden Zwischen- und Notfallen bei der Tumortherapie fuhren. Das uberarbeitete Kompendium hilft die jeweilige Situation rasch und sicher einzuschatzen. Im allgemeinen Teil werden umfassend die Themen Pradisposition, Pravention, Schadigungstyp, allgemeine Massnahmen im Umgang mit Paravasaten, spezifische Antidota und Dokumentation behandelt. In der 2. Auflage wurde die wissenschaftliche Information des allgemeinen Teils und der Substanzen auf den aktuellen Stand gebracht. Der substanzspezifische Teil enthalt detaillierte Handlungsanleitungen fur uber 50 Zytostatika, um gezielt Massnahmen einzuleiten. Vordrucke fur ein Paravasate-Set, UEbersichtstabellen, Dokumentationsboegen und Patientenaufklarungen sowie eine CD-ROM liegen zur Unterstutzung fur die klinische Praxis bei. Das Buch ist aus dem Konsens einer interdisziplinaren Arbeitsgruppe entstanden, die samtliche publizierte Literatur gesammelt und systematisch ausgewertet hat.

The extravasation of cytotoxic agents can result in severe local tissue damage and medical emergencies during tumour therapy. This revised compendium is intended to help clinicians assess any situation speedily and with certainty. The general section of the book includes topics such as predisposition, prevention, type of harm, general measures in handling extravasated drugs, specific antidotes, and documentation. In the 2nd edition, the scientific information contained in the general section and relating to the actual substances has been updated. The substance specific part of the book includes detailed instructions on handling more than 50 cytotoxic drugs, to initiate targeted measures. Templates for an extravasation set, overview tables, documentation sheets, and patient information, as we as a CD-ROM are included to support clinical practice. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic.