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This volume explores the role of proteases in various catalytic
classes and cellular processes associated with cancer. The chapters
in this book cover topics such as encoding proteolytic enzymes,
cleavage sites of proteases, functional catalytic domains of MMPs,
zymography, angiogenesis and lymphangiogenesis, genetic and
epigenetic alterations of metallopeptidases, and methods to target
metalloproteinases. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting edge, Proteases and Cancer: Methods and
Protocols is a valuable resource for clinical researchers across
numerous fields such as molecular and cellular biology, oncology,
biochemistry, and chemistry. This book is also useful for PhD
students in the various disciples of health sciences.
This volume explores the role of proteases in various catalytic
classes and cellular processes associated with cancer. The chapters
in this book cover topics such as encoding proteolytic enzymes,
cleavage sites of proteases, functional catalytic domains of MMPs,
zymography, angiogenesis and lymphangiogenesis, genetic and
epigenetic alterations of metallopeptidases, and methods to target
metalloproteinases. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting edge, Proteases and Cancer: Methods and
Protocols is a valuable resource for clinical researchers across
numerous fields such as molecular and cellular biology, oncology,
biochemistry, and chemistry. This book is also useful for PhD
students in the various disciples of health sciences.
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