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Genetics and Genomics in Medicine (Paperback): Tom Strachan, Anneke Lucassen, Patrick Chinnery Genetics and Genomics in Medicine (Paperback)
Tom Strachan, Anneke Lucassen, Patrick Chinnery
R515 R477 Discovery Miles 4 770 Save R38 (7%) Ships in 5 - 10 working days

Genetics and Genomics in Medicine is a new textbook written for undergraduate students, graduate students, and medical researchers that explains the science behind the uses of genetics and genomics in medicine today. Rather than focusing narrowly on rare inherited and chromosomal disorders, it is a comprehensive and integrated account of how genetics and genomics affect the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights into its molecular basis and approaches to its detection gained from cancer genomics. Specific topics, including multiple examples of clinical disorders, molecular mechanisms, and technological advances, are profiled in boxes throughout the text.

Human Molecular Genetics (Hardcover, 5th New edition): Tom Strachan, Andrew Read Human Molecular Genetics (Hardcover, 5th New edition)
Tom Strachan, Andrew Read
R4,571 Discovery Miles 45 710 Out of stock

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features: Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.

Human Molecular Genetics (Paperback, 3rd Revised edition): Tom Strachan, Andrew Read Human Molecular Genetics (Paperback, 3rd Revised edition)
Tom Strachan, Andrew Read
R1,475 R1,301 Discovery Miles 13 010 Save R174 (12%) Out of stock


Contents:
Section 1. The Basics 1. DNA Structure and Gene Expression 2. Chromosome Structure and Function 3. Cells and Development 4. Genes in Pedigrees and Populations 5. Amplifying DNA: PCR and Cell-based DNA Cloning 6. Nucleic Acid Hybridization: Principles and Applications 7. Analyzing DNA and Gene Structure, DNA Variation and Expression Section 2. The Human Genome and it's Relationship to Other Genomes 8. Genome Projects and Model Organisms 9. Organization of the Human Genome 10. Human Gene Expression 11. Instability of the Human Genome: Mutation and DNA Repair 12. Our Place in the Tree of Life Section 3. Mapping and Identifying Disease Genes and Mutations 13. Genetic Mapping of Mendelian Characters 14. Identifying Human Disease Genes 15. Mapping and Identifying Genes Conferring Susceptibility to Complex Diseases 16. Molecular Pathology 17. Cancer Genetics 18. Genetic Testing in Individuals and Populations Section 4. New Horizons: Into the 21st Century and Beyond 19. Beyond the Genome Project: Functional Genomics, Proteomics and Bioinformatics 20. Genetic Manipulation of Cells and Animals 21. New Approaches to Treating Disease.

Human Molecular Genetics (Paperback, 5th New edition): Tom Strachan, Andrew Read Human Molecular Genetics (Paperback, 5th New edition)
Tom Strachan, Andrew Read
R950 R851 Discovery Miles 8 510 Save R99 (10%) Out of stock

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology. Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features: Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.

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