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The liquisolid systems are generally considered as acceptably
flowing and compressible powdered forms of liquid medications (that
implies liquid lipophilic (oily) drugs, or water-insoluble solid
drugs dissolved in suitable water-miscible nonvolatile solvent
systems). Such liquid medication may be converted into a dry
looking, non-adherent, free flowing, and readily compressible
powders by a simple admixture with selected powder excipients
referred to as the carrier and coating materials. We sincerely hope
that this book will helpful to student as well as industry and
academic professionals involved in pharmaceutical and other related
science.
The present study has been a satisfactory attempt to formulate
microparticulate system for colon targeted delivery of albendazole
using natural polysaccharides sodium alginate and chitosan.
Targeted drug delivery to the colon, by means of combination of one
or more controlled release mechanisms, hardly releases drug in the
upper part of the GIT but releases in the colon following oral
administration. Specifically delivering drug to the colon, a lot of
benefits would be acquired in terms of improving safety and
reducing toxicity when treating local or systemic chronic diseases.
We sincerely hope that this book will helpful to student as well as
industry and academic professionals involved in pharmaceutical and
other related science.
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