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Immune Infertility - Impact of Immune Reactions on Human Fertility (Hardcover, 2nd ed. 2017): Walter K. H. Krause, Rajesh K. Naz Immune Infertility - Impact of Immune Reactions on Human Fertility (Hardcover, 2nd ed. 2017)
Walter K. H. Krause, Rajesh K. Naz
R3,860 R3,483 Discovery Miles 34 830 Save R377 (10%) Ships in 10 - 15 working days

This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

Drugs Compromising Male Sexual Health (Paperback, 2008 ed.): Walter K. H. Krause Drugs Compromising Male Sexual Health (Paperback, 2008 ed.)
Walter K. H. Krause
R3,579 Discovery Miles 35 790 Ships in 7 - 11 working days

This concise drug guide lists 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, which show documented untoward effects on the male sexual organs and their functions. All substances are listed in user-friendly alphabetical order with a uniform structure throughout the book. Each listing includes evidence-based information with up-to-date references and all studies mentioned are evaluated and categorized according to study and sample types. This unique compendium provides more detailed information on each drug than any other standard pharmacology title.

Cutaneous Manifestations of Endocrine Diseases (Hardcover, 2009 ed.): Walter K. H. Krause Cutaneous Manifestations of Endocrine Diseases (Hardcover, 2009 ed.)
Walter K. H. Krause; Contributions by N. Stutz; Foreword by Serge Jabbour
R2,308 Discovery Miles 23 080 Out of stock

Skin lesions are often the first sign for an endocrine disease. Their description is thus of relevance for early diagnosis and treatment of endocrine disease for specialists in endocrinology as well as in dermatology.

Lavishly illustrated, this book describes the clinical and histological features of skin lesions observed in endocrine diseases. All features are reader-friendly structured and written in the language of dermatologists in order to enable a simple association between the features observed and the endocrine etiology.

Immune Infertility - Impact of Immune Reactions on Human Fertility (Paperback, Softcover reprint of the original 2nd ed. 2017):... Immune Infertility - Impact of Immune Reactions on Human Fertility (Paperback, Softcover reprint of the original 2nd ed. 2017)
Walter K. H. Krause, Rajesh K. Naz
R3,639 Discovery Miles 36 390 Out of stock

This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

Immune Infertility - The Impact of Immune Reactions on Human Infertility (Paperback, 2009 ed.): Walter K. H. Krause, Rajesh K.... Immune Infertility - The Impact of Immune Reactions on Human Infertility (Paperback, 2009 ed.)
Walter K. H. Krause, Rajesh K. Naz
R4,365 R4,129 Discovery Miles 41 290 Save R236 (5%) Out of stock

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2-30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

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