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Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces (Hardcover)
Loot Price: R6,317
Discovery Miles 63 170
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Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces (Hardcover)
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Total price: R6,337
Discovery Miles: 63 370
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Biosensors are finding increasing applications in different areas.
Over the last few years the areas where biosensors may be used
effectively has increased dramatically. This book like the previous
four books on analyte-receptor binding and dissociation kinetics by
this author addresses the often neglected area. The kinetics of
binding and dissociation in solution to appropriate receptors
immobilized on biosensor surfaces occurs under diffusional
limitations on structured surfaces. The receptors immobilized on
the biosensor surface contribute to the degree of heterogeneity on
the sensor chip surface.
The fractal analysis examples presented throughout the book provide
a convenient means to make quantitative the degree of heterogeneity
present on the sensor surface, and relates it to the binding and
dissociation rate coefficients. The fractal dimension is a
quantitative measure of the degree of heterogeneity present on the
biosensor surface. The book emphasizes medially-oriented examples.
The detection of disease-related analytes is also emphasized. The
intent being that if intractable and insidious diseases are
detected earlier, they will be controlled better, eventually
leading to a better prognosis. Chapter 3 is a new chapter that
emphasizes enhancing the relevant biosensor performance parameters
such as sensitivity, stability, selectivity, response time, etc.
As usual, as done in previous books by this author, the last
chapter provides an update of the economics involved in biosensors,
and the difficulties encounters in starting-up a biosensor company.
- Modelling of binding and dissociation kinetics of
analyte-receptor reactions on biosensor surfaces: provides physical
insights into these reactions occurring on biosensor surfaces. Very
few researchers even attempt to analyze the kinetics of these types
of reactions.
- Fractal analysis used to model the binding and dissociation
kinetics: original and unique approach.
- Economic analysis provided in the last chapter: helps balance the
book; besides providing much-needed information not available in
the open literature.
- Emphasis on improving biosensor performance parameters: helps
make biosensors better.
- Empahsis on medically-related analytes: helps in prognosis of
diseases.
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