Treatment of articular cartilage pathology in the knees of young
and active patients is a challenging and controversial issue.
Biologic Knee Reconstruction: A Surgeon's Guide is a how-to,
step-by-step guide that addresses the evaluation and management of
this unique patient population. Â Internationally renowned
cartilage experts Dr. Brian J. Cole and Dr. Joshua D. Harris, along
with their contributors, present information on normal and abnormal
history and physical examination. The reader will learn proper
decision-making using a patient-centered approach of treatment,
increasing the likelihood of a successful outcome. In addition to
radiographic assessment of articular cartilage, Biologic Knee
Reconstruction discusses the use of biomarkers, defect
classification, and patient-reported and surgeon-measured outcomes.
Aggressive nonsurgical medical management, including medications,
injections, physiotherapy, and rehabilitation, is also presented.
 Biologic Knee Reconstruction also discusses the management
of concomitant pathologies such as malalignment, meniscal
deficiency, and ligamentous instability. Selection of surgical
cartilage restorative treatment options is multifactorial,
requiring consideration of several patient-, knee-, and
defect-specific issues. All contemporary open and arthroscopic
cartilage techniques are presented in detail with high resolution
figures. A unique feature of Biologic Knee Reconstruction is the
presentation of several chapters discussing non-medical issues
highly pertinent to the advancement and future of this field:
funding of research and cost of new advanced technologies,
regulation of advanced cellular, tissue, and genetic technologies,
evidence-based medicine and clinical trial design and conduct, and
the ethics of allograft tissues and stem cell use. Â
Features: Technique preference cards from the experts performing
cartilage surgery Patient education information The most up-to-date
descriptions of advanced cartilage techniques Unique chapters not
covered in books elsewhere, including: Biomarkers Patient-reported
outcomes assessment Newer injection techniques (PRP, stem cells)
One- and two-stage open and arthroscopic techniques using
chondrocyte- and stem cell based cell therapies Costs and public
and private funding of research Barriers to high-quality randomized
trials Governmental regulation and availability/accessibility to
patients Gene therapy and tissue engineering Ethics of articular
cartilage surgery with stem cells, ex-vivo cell manipulation, and
juvenile tissue sources  With the most up-to-date content
and step-by-step methods for surgical procedures, Biologic Knee
Reconstruction: A Surgeon's Guide is the perfect addition to the
bookshelf of the orthopedic surgeon, cartilage researcher, sports
physical therapist, or athletic trainer who evaluates and manages
this unique patient population.
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