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Animal Clinical Chemistry - A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition (Hardcover, 2nd edition)
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Animal Clinical Chemistry - A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition (Hardcover, 2nd edition)
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10+ Years' of Updates Since First Edition Newcomers to the animal
clinical chemistry and toxicology fields quickly find that the same
rules of human medicine do not always apply. Following in the
footsteps of its standard-setting first edition, Animal Clinical
Chemistry: A Practical Handbook for Toxicologists and Biomedical
Researchers, Second Edition collates information widely dispersed
in journals and book chapters, focusing on the most-relevant
literature to experimental toxicology and its distinction from
human medicine. Expands Discussion of Troponins, Lipids, and
Electrolytes In addition to tests recommended by regulatory
authorities, this globally relevant resource includes information
about clinical chemistry tests as well as hepato-, nephro-,
cardio-, and endocrine toxicity. It also covers pre-analytical and
analytical variables, which play a far more important role with
interpreting data from animal studies as compared to human studies
when variables can be well-controlled with less physiological
effect. Furthermore, this edition takes its discussion of
biomarkers to the next level, exploring newer and related
investigations, such as metabolomics/NMR and multiplex technology.
Under the editorial guidance of G.O. Evans, a recognized field
authority, the book presents background information on the
selection and application of biochemical tests in preclinical
safety assessment studies. It also assesses specific organ
toxicity, such as in the liver, kidney, and thyroid, along with
regulatory requirements and statistical approaches. Careful to
avoid delving into overly complex detail, this text is a
comprehensive, practical reference ideal for new entrants to the
field. However, its broad scope and depth also make it suitable for
more seasoned scientists and toxicologists.
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