Conceived in the early 1970s to study the phenomenology,
diagnosis, genetics, and clinical course of depression, the NIMH
Collaborative Depression Study (CDS) has influenced research and
practice since its inception. Clinical Guide to Depression and
Bipolar Disorder: Findings From the Collaborative Depression Study
summarizes key findings from the study and the related literature
to provide comprehensive and up-to-date knowledge on the course and
outcome of illness in mood disorders. Nowhere else can clinicians
find such detailed longitudinal data, combined with astute clinical
analysis of the current research. The volume offers:
- Historical background on how psychodynamic psychiatry was
overtaken by psychobiological perspectives, and the challenges and
controversies that gave rise to the CDS, providing the context
necessary to understand the profession's development to the present
day.- A wealth of information on nosology, natural history,
phenomenology, and treatment response in depressive and bipolar
disorders.- Detailed descriptions of the study methods employed,
providing information and insights that will assist researchers in
the longitudinal design of prospective cohort studies.-
Comprehensive review of outcomes in mood disorder, including
delineation of the long-term course of bipolar I, bipolar II, and
unipolar major depressive disorders, the implications of which will
continue to be instrumental in the development of psychiatric
nosology and indispensable to clinicians engaged in assessment and
treatment.- Critical information clinicians need in order to read
the clinical signs in their patients and predict the "switch" from
unipolar to bipolar disorder.- A fascinating review of the
evolution of diagnostic thinking about the role of anxiety in mood
disorders, and the contributions of the CDS to the newly published
DSM-5(R).
Each chapter is accompanied by a time-saving summary, as well as
a section on clinical implications that translates the findings
into practical points and key recommendations clinicians need to
know to provide optimal care. Psychiatrists, clinical
psychologists, residents, and fellows will turn to Clinical Guide
to Depression and Bipolar Disorder: Findings From the Collaborative
Depression Study to better understand the course and outcome of
their patients' mood disorders and, ultimately, to improve their
clinical skills.
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