Pain is a response of the body to the action of injuring stimuli.
Notwithstanding an unpleasant experience, it appears to be an
important component of the defence system of the organism and a
permanent regulator of homeostatic reaction. The organism's
reaction to pain is a multi-component one and involves
sensory-discriminative, emotional-affective and cognitive
characteristics. Clinically, neuropathic pain is characterised by
spontaneous ongoing or shooting pain and evoked amplified pain
responses after nocuous or innocuous stimuli. The study of pain,
therefore, and search for the treatment strategies have a paramount
role in modern neurobiology. Numerous anatomy-physiological studies
have revealed a number of brain structures involved in the shaping
of pain and endogenous analgesia. This book presents and examines
current research discovered in a behavioural study of 'non-opioid'
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