The concept of using photochemical probes in the study of
biological systems was developed by Westheimer who published the
first photoaffinity labeling experiments more than twenty years ago
(J.Bio1. Chem. 237, (1962) 3006). Since then the concept has been
used successfully in various areas of biochemistry and recently
several new interesting and exciting aspects of the concept have
been developed. It is the general opinion by scientists in the
"field" that the full potential of photochemical probes in
biochemical studies has far from been exploited yet. This is mostly
due to the interdisciplinary character of the concept involving
photochemistry, synthetic chemistry as well as
biochemistry/molecular biology. The perspective of the NATO
advanced workshop on "Photochemical Probes in Biochemistry", held
in Holte (Copenhagen) Denmark 14-19, August, 1988, was several
fold. The workshop was to give an account of the "state of the art"
of using photochemical probes in biochemistry as well as to bring
together specialists in photochemistry, syn thetic chemistry and
molecular biology in order to analyze advantages as well as the
inherent problems and pitfalls of the concept and provide
suggestions and guidelines for fu ture research. Furthermore, it
is the hope of the editor that the present publication which gives
an account of the lectures presented at the workshop, will provide
an introduction to scientists who are not familiar with
photochemical probes, but to whom these could help answer central
and pertinent questions.
General
Imprint: |
Springer
|
Country of origin: |
Netherlands |
Series: |
NATO Science Series C, 272 |
Release date: |
April 1989 |
First published: |
1989 |
Editors: |
Peter E. Nielsen
|
Dimensions: |
250mm (L) |
Format: |
Hardcover
|
Pages: |
320 |
Edition: |
1989 ed. |
ISBN-13: |
978-0-7923-0171-4 |
Categories: |
Books
|
LSN: |
0-7923-0171-4 |
Barcode: |
9780792301714 |
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